Human SNPs Reveal No Evidence of Frequent Positive Selection
نویسندگان
چکیده
منابع مشابه
Human SNPs reveal no evidence of frequent positive selection.
We compared the single-nucleotide polymorphisms (SNPs) in humans in 182 housekeeping and 148 tissue-specific genes. SNPs were divided into rare and common polymorphisms based on their frequencies. We found that housekeeping genes tend to be less polymorphic than tissue-specific genes for both rare and common SNPs. Using mouse as a second species for computing sequence divergences, we found no e...
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ژورنال
عنوان ژورنال: Molecular Biology and Evolution
سال: 2005
ISSN: 0737-4038,1537-1719
DOI: 10.1093/molbev/msi240